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Patented Nanobubble Technology · Available for Licensing

Simpler Generation.
Broader Application.
Proven Results.

NanoBurstX has developed and patented a nanobubble generation process that is simpler to implement, lower in energy demand, and designed to integrate into existing systems. The technology is commercially deployed and available for licensing.

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Trusted By Industry Leaders
Norwegian Cruise Line — Industry Partner
Solmetex — Exclusive Licensee
HTRI — Exclusive Worldwide Licensee
Microchip Technology — Deployment Partner
Roebic Laboratories — Exclusive Licensee
The NanoburstX Advantage

A Fundamentally Different Approach to Nanobubble Generation

I 2
Air Fluid Innovation, Inc. has developed NanoBurstX TM, a breakthrough in nanobubble generation
that uses chemically initiated Nanobubbles (CINB) technology to replace
traditional mechanical methods. Unlike systems reliant on pressurization,
cavitation, or membranes, NanoBurstX TM employs proprietary
vapor-phase infusion to rapidly produce highly stable nanoscale bubbles.
Independent validation at the University of California, Irvine confirmed a mean
size of ~66 nm with stability exceeding 192 hours from a single 3-minute
infusion, with additional verification from NJIT, Cornell University, and
Malvern Panalytical. The process is low energy and designed for simple
integration into existing systems, enabling rapid adoption without complex
infrastructure. I 2 Air Fluid Innovation operates a licensing model, providing
patented technology, know-how, and design support, allowing their partners to
integrate NanoBurstX TM into existing platforms while maintaining
control of manufacturing and margins

CINB

Patented Process

~200nm

Bubble Size

192hr

Stability Verified

7+

Years Deployed

4+1

Granted Patents + Application

13

University Collaborations

8

Government Studies

Who This Is For

If Nanobubbles Are Part of Your Strategy, Evaluate CINB First

Whether you already generate nanobubbles or are exploring them for the first time, chemical initiation unlocks capabilities that mechanical generation methods cannot.

Existing Nanobubble Companies

Expand Your Capability

Already generating nanobubbles through mechanical methods? CINB’s chemical initiation unlocks finer size distribution, longer stability, configurable treatment agents, and application versatility that mechanical generation cannot achieve. License CINB to extend what your platform can do.

Hardware & System Companies

Add Nanobubble Capability

Looking to differentiate your technology with nanobubbles? CINB integrates into existing fluid systems at low energy, low pressure, and without specialized infrastructure, so you add nanobubble capability without redesigning your platform.

End Users & Operators

Build Your Own Capability

Dependent on a single nanobubble supplier? License CINB to vertically integrate, reduce supplier dependency, and gain strategic control over your nanobubble capability, without building mechanical generation infrastructure.

Displace a Cost You Already Carry

Chemical Additive and Consumable Suppliers

Operating a chemical program that CINB could reduce or replace? Licensees in beverage CIP, hydraulic fracturing, and wastewater treatment are using CINB to reduce biocide volume, cut caustic cycle frequency, and lower coagulant requirements. If your customers are evaluating CINB, licensing it positions you ahead of displacement rather than behind it.

Wherever you sit in the value chain — generating nanobubbles today, looking to add the capability, managing supplier dependency, or protecting a chemical program from displacement — CINB offers capabilities that mechanical generation methods do not. We encourage you to evaluate the difference before committing to a conventional approach.

Intellectual Property

A Layered IP Portfolio

Four granted US patents, a provisional patent application advancing to formal filing, a registered trademark, and extensive proprietary trade secrets and know-how.

Granted Infusion Patents

US 10,471,166 · US 10,646,608 · US 11,504,442

Three granted US patents covering iodine-laden gas disinfection systems with progressively refined control, sensor integration, and automated calibration, plus mercury and heavy metal wastewater treatment using biocatalytic media. Enforceable through 2037 to 2038.

3 Granted Patents

Nanobubble Generation Platform

Provisional Application 63/857,818 · Filed Aug 5, 2025

Provisional patent application covering the CINB process, a non-mechanical, diffusion-based system for generating nanobubbles using configurable carrier gases and chemical agents. Advancing to formal utility filing. Establishes the priority date for the central enabling technology across all approved verticals.

Provisional Application

Granted Biological Patent

US 12,312,267

Mereduce™ is a patented biological platform designed to transform toxic metals, denude microplastic surfaces, and enhance microbial performance across wastewater, agriculture, and aquaculture. Using specialized microbial pathways, growth and delivery methods, it transforms and immobilizes metals such as mercury, reducing toxicity, improving effluent quality, and supporting regulatory compliance. Its bioactive consortia also disrupt microplastic surface coatings, lowering contaminant transport and improving downstream removal. In agricultural and aquacultural systems, Mereduce™ acts as a probiotic, strengthening microbial balance and nutrient cycling. Deployed standalone or with NanoBurstX™, it provides a scalable, low-chemical solution for environmental remediation and system optimization aligned with sustainability-driven operations. Enforceable through 2045.

Granted Patent

Trade Secrets and Proprietary Know-How

The NanoBurstX portfolio extends beyond patents and public filings. The specific process parameters, chemical agent configurations, infusion protocols, carrier gas formulations, and system integration know-how are not disclosed in any public document. Licensees receive access to proprietary knowledge developed over decades of research and commercial deployment that cannot be replicated from published literature or patent claims alone. This layer of protection is independent of any single patent outcome.
Approved Verticals

Illustrative Applications & Markets

Radiological Applications

Nanobubble-infused fluids as contrast adjuncts

Available for Licensing

Shale Fracking Additives

Iodine and ammonium nanobubbles for penetration

Available for Licensing

Membrane Fouling

Integration with RO, UF, and NF systems

Available for Licensing

Medical & Therapeutic Water

Burn/wound irrigation, hydrotherapy, cleansing

Available for Licensing

Recreational & Commercial Water

Pools, spas, wellness centers, fountains

Available for Licensing

Wastewater Treatment

Aeration, septic, mercury/toxic-metal treatment

Available for Licensing

CIP / Beverage Bottling

CINB-treated water reduces cleaning cycle time, chemical volume, and biofilm in low-flow line geometry

Available for Licensing

UV Purification Sleeve Fouling

Fouling mitigation on UV sleeves

Available for Licensing

Proven in the Field

Featured Deployments

Heat Exchangers · Process Equipment

HTRI, Exclusive Worldwide Licensee

Exclusive worldwide provider since 2014

HTRI (Heat Transfer Research, Inc.) holds an exclusive worldwide license to apply I 2’s vapor infusion technology within heat exchangers, associated piping systems, and water processing applications. The partnership originated from Michael Radicone’s presentation at the 2013 International Conference on Heat Exchanger Fouling and Cleaning in Budapest.

Successful implementations include cruise shipping, offshore drilling, geothermal systems, and aquaculture. In 2024, Michael received the Mike Ackrill Award from the UK Heat Transfer Society.

Exclusive Licensee
Marine · Heat Exchanger Fouling (via HTRI)

Norwegian Sun, Engine Coolers

8 years foul-free

Both sets of main engine coolers (forward and aft) operated without cleaning for 26+ months. First Engineer reported all four low-temperature coolers in good condition. No biological fouling. No mineral fouling. Zero unplanned maintenance.

Active
Energy · Offshore (via HTRI)

Semi-Submersible Drilling Ship

7 years foul-free

8 thruster coolers (3,800 kW each), 8 main engine coolers (5,060 kW each), 4 miscellaneous exchangers, 10 vapor infusion systems. Thruster #6 operated continuously for 3 months and outperformed recently cleaned units at 100% load.

Active

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